A single step process for the synthesis of quinoline-3-carboxylic acid was developed from 2’-amino acetophenons. With this method a Key
intermediate of ciprofloxacin is prepared.
The physico-chemical properties of the biodiesel prepared from Sweet almond seed oil was determined and discussed in accordance with ASTM D6751 and DIN 14214 standards for biodiesel. The influence of the fatty acid composition and functional groups on the fuel related propertieswas carried out using Gas Chromatography-Mass Spectrometry (GC-MS) technique and Fourier Transform Infrared Radiation (FTIR)spectroscopy analyses respectively. The presence of C-H indicates the presence of properties as pour and cloud point that affect the performance of biodiesel during cold weather engine operations but the biodiesel sample was found to contain more C=C that can cause it to remain in liquid state with tendency of poor storage stability. It was equally observed that the Sweet Almond Seed Oil Methyl Ester (SASOME) is mainly composed of monounsaturated fatty acid and expected to possess low values for density, viscosity, heating value and thermal efficiency with average cetane number. This woul...
The variation in the Physico Chemical properties of Beta Asarone when the temperature is raised is studied here. The Solvent effect has alsobeen calculated with 2 solvents-water and ethanol by (Polarizable continuum Model (PCM) method where a solute cavity is created by a set ofover lapping spheres and computes the energy in solution. The electrostatic interactions of molecules are studied using their Mulliken charge distribution. SCF Energy, Molecular electrostatic Potential mapping, Dipole moment, Ionization Potential and Thermal properties are also studied. Beta Asarone which is the reported toxic constituent of Acorus calamus might undergo variations with higher temperature and also when it is in solution. The study of variations in solution is challenging and here the quantum mechanical calculations are performed in two different solutions to test for any variations of Beta Asarone in solution.
The quality of pharmaceuticals is always a matter of global concern because counterfeit medications with substandard quality are increasingly detected worldwide, the reason for which can be that these drugs may not have been subjected to strict approval processes by relevant regulatory agencies. So, in order to ensure the requisite quality, it should be mandatory for the drug manufacturers to analyze their products during each level of manufacturing and processing. Moreover some multinational brands are so costly and thus unaffordable to common people and comparatively local brands of same generic are available at much lower prices. But to select one product from several generic drugproducts of same active ingredients is the cause for concern for the common people. So, every effort should be done to make these drugs chemically and pharmaceutically equivalent in every aspect as the branded drugs which can only be possible if proper quality control guidelines are being followed during ...
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