Synthesis and Antitubercular Screening of 2-Chloro-N-(3-Cyano-4,5,6,7-Tetrahydro-1- Benzothiophen-2-Yl)Acetamide Clubbed Substituted 5-Phenyl-1,3,4-Oxadiazole-2- Thiol
Reactions of 2-chloro-N-(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)acetamide with substituted 5-phenyl-1,3,4-oxadiazole-2 thiol gave N-
(3-cyano-4,5,6,7-tetrahydro-1-benzothiophen-2-yl)-2-aryl-[(5-phenyl-1,3,4-oxadiazol-2-yl)sulfanyl]acetamide were synthesized and assessed for
their efficacy as antitubercular agents against tuberculosis H37Rv. The structural assignments of the new products were done on the basis ofInfrared radiation (IR), Proton nuclear magnetic resonance (1H-NMR) and elemental analysis.
Comments
Post a Comment